Dennis Nthiga Kirema.
Computational biology / Nairobi, working worldwide

Your lab has the data. I do the analysis.

Freelance bioinformatics for labs and companies without an in-house analyst. Send me your counts matrix, your FASTQ files or your public cohort, and get back results you can put in a manuscript.

Cancer transcriptomics, survival modelling, structural bioinformatics and reproducible pipelines. Fixed scope, fixed price, agreed before any work starts.

Fig. 1. Volcano plot, simulated data for illustration. Points coloured by direction of change, grey below the significance threshold. Every figure I deliver comes with the script that produced it.
What I deliver

Three things I do well, priced up front

Each engagement is a written scope with a fixed fee. Fifty percent on start, fifty on delivery. If your work does not fit these shapes, tell me what it looks like and I will quote it.

RNA-seq differential expression

From raw counts or FASTQ to a result you can defend to a reviewer.

  • QC and normalisation report
  • DE tables with adjusted p-values
  • Volcano, heatmap, PCA figures
  • Pathway enrichment
  • Annotated analysis script
from USD 4507 days

Survival and public cohort analysis

TCGA, CGGA and GEO cohorts assembled, modelled and cross-checked.

  • Cohort assembly and cleaning
  • Kaplan-Meier and Cox models
  • Signature scoring
  • Replication in a second cohort
  • Methods paragraph you can reuse
from USD 3505 days

Reproducible pipeline build

Your one-off analysis turned into something your whole lab can rerun.

  • Nextflow or Snakemake workflow
  • Containerised environment
  • Test data and worked example
  • README and handover session
  • Source code, yours to keep
from USD 70014 days
How it works

No surprises, in four steps

Most projects start with a twenty minute call and a look at your data structure. You will know the price and the delivery date before you commit anything.

STEP 01

Tell me the question

What you measured, what you want to know, and what the data looks like right now.

STEP 02

Written scope

A one page statement of work: deliverables, fee, timeline, revision rounds. You sign it or you do not.

STEP 03

Analysis

I work in the open with a short progress note midway, so nothing arrives as a shock at the end.

STEP 04

Handover

Figures, tables, a written interpretation and the code. Plus a call to walk you through it.

Background

Who is actually doing your analysis

I am a computational biologist based in Nairobi. My MSc research at Kenyatta University characterises vascular normalisation in low-grade glioma across three independent cohorts, using R and Bioconductor throughout: differential expression, signature scoring, immune deconvolution and multivariable survival modelling.

Before that I spent a research placement at the Bioinformatics Institute, A*STAR Singapore, on an SIPGA award, working on protein-ligand interaction analysis and cardiac ion channel liability for antimicrobial compounds. That is where I learned to be careful with structural data.

I also co-founded NORYTA Limited, a Kenyan technology and scientific solutions company, where I lead the data side. For larger builds that need a team and a contracting entity, I bring NORYTA in. For analysis work, you are hiring me.

I am comfortable working as a subcontractor to consultancies and sequencing providers, under your brand and without public credit, if that is what the project needs.

Focus
Cancer transcriptomics, survival analysis, structural bioinformatics
Stack
R and Bioconductor, Python, Bash and Linux, Git, Nextflow
Training
MSc Medical Biochemistry and BSc Biotechnology, Kenyatta University
Award
A*STAR SIPGA, Bioinformatics Institute, Singapore
Payment
Wise, Payoneer, PayPal, bank transfer. Invoices in USD, EUR or GBP
Zone
EAT, UTC+3. Overlaps with Europe, Asia and US mornings
Contact

Send me the awkward dataset

Tell me what you have and what you need to know. I will reply within one working day with either a quote or an honest referral if it is not my area.

Email dennis.kirema17@gmail.com
GitHub github.com/kND-17
Phone +254 704 893 211
WhatsApp +254 704 893 211
Based in Nairobi, Kenya